Philippe J Sansonetti Selected Research

Bacillary Dysentery (Shigellosis)

1/2021	Structural Insights of Shigella Translocator IpaB and Its Chaperone IpgC in Solution.
1/2019	Shigella-mediated immunosuppression in the human gut: subversion extends from innate to adaptive immune responses.
1/2018	Human Enteric α-Defensin 5 Promotes Shigella Infection by Enhancing Bacterial Adhesion and Invasion.
1/2018	MUB40 Binds to Lactoferrin and Stands as a Specific Neutrophil Marker.
1/2017	Identification of novel substrates of Shigella T3SA through analysis of its virulence plasmid-encoded secretome.
4/2016	A Synthetic Carbohydrate Conjugate Vaccine Candidate against Shigellosis: Improved Bioconjugation and Impact of Alum on Immunogenicity.
2/2016	PI5P Triggers ICAM-1 Degradation in Shigella Infected Cells, Thus Dampening Immune Cell Recruitment.
6/2014	Non-stoichiometric O-acetylation of Shigella flexneri 2a O-specific polysaccharide: synthesis and antigenicity.
10/2013	Virulent Shigella flexneri affects secretion, expression, and glycosylation of gel-forming mucins in mucus-producing cells.
9/2012	Preventing acute gut wall damage in infectious diarrhoeas with glycosylated dendrimers.

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Philippe J Sansonetti Research Topics

Disease

26	Infections 01/2022 - 01/2002
23	Bacillary Dysentery (Shigellosis) 01/2021 - 05/2002
16	Inflammation (Inflammations) 01/2018 - 04/2002
3	Neoplasms (Cancer) 11/2019 - 08/2017
3	Bacterial Infections (Bacterial Infection) 04/2014 - 07/2002
3	Dysentery 09/2011 - 06/2002
2	Growth Disorders 01/2020 - 01/2018
2	Dysbiosis 11/2019 - 10/2017
2	Rhinoscleroma 01/2018 - 04/2013
2	Pneumonia (Pneumonitis) 07/2015 - 06/2002
2	Crohn Disease (Crohn's Disease) 10/2005 - 03/2003
1	Communicable Diseases (Infectious Diseases) 04/2022
1	Ascorbic Acid Deficiency (Vitamin C Deficiency) 10/2021
1	Aberrant Crypt Foci 11/2019
1	Colonic Neoplasms (Colon Cancer) 12/2018
1	Body Weight (Weight, Body) 01/2018
1	Hypercholesterolemia 01/2018
1	Dehydration (Water Stress) 12/2017
1	Obesity 10/2017
1	Hypoxia (Hypoxemia) 01/2016
1	Porcine Reproductive and Respiratory Syndrome (PRRS) 01/2016
1	Graft vs Host Disease (Graft-Versus-Host Disease) 02/2011
1	Ischemia 04/2010
1	Intestinal Diseases (Diseases, Intestinal) 04/2010
1	Diarrhea 02/2008

Drug/Important Bio-Agent (IBA)

10	VaccinesIBA 01/2019 - 06/2002
8	Proteins (Proteins, Gene)FDA Link 01/2021 - 06/2002
5	Interleukin-8 (Interleukin 8)IBA 09/2012 - 04/2002
4	Virulence Factors (Pathogenicity Factors)IBA 01/2018 - 01/2002
4	CytokinesIBA 01/2016 - 06/2002
4	Peptidoglycan (Murein)IBA 02/2007 - 03/2003
3	Polysaccharides (Glycans)IBA 04/2022 - 02/2006
3	Conjugate VaccinesIBA 04/2022 - 02/2009
3	Immunoglobulin A (IgA)IBA 01/2020 - 07/2002
3	Capsules (Microcapsules)IBA 01/2018 - 03/2015
3	phosphatidylinositol 5-phosphateIBA 12/2013 - 03/2006
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 01/2006
2	Biomarkers (Surrogate Marker)IBA 11/2019 - 01/2018
2	CarbohydratesIBA 04/2016 - 02/2009
2	O Antigens (O Antigen)IBA 06/2014 - 02/2009
2	Type III Secretion SystemsIBA 04/2014 - 04/2011
2	LipidsIBA 12/2013 - 09/2011
2	Interleukin-6 (Interleukin 6)IBA 09/2012 - 06/2002
2	Phosphatidylinositols (Phosphatidylinositol)IBA 09/2011 - 10/2002
2	NucleotidesIBA 04/2010 - 04/2002
2	Peptides (Polypeptides)IBA 04/2008 - 10/2005
2	LipopolysaccharidesIBA 02/2008 - 06/2007
2	Leucine (L-Leucine)FDA Link 02/2007 - 04/2002
2	L-Ala-gamma-D-Glu-meso-diaminopimelic acidIBA 11/2005 - 10/2005
2	ChemokinesIBA 09/2004 - 09/2003
2	Interleukin-18 (Interleukin 18)IBA 06/2002 - 01/2002
1	HaptensIBA 04/2022
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 10/2021
1	Phenobarbital (Luminal)FDA Link 11/2019
1	DNA (Deoxyribonucleic Acid)IBA 11/2019
1	INTERCEEDIBA 12/2018
1	LactoferrinIBA 01/2018
1	Biological ProductsIBA 01/2018
1	DefensinsIBA 01/2018
1	ChylomicronsIBA 01/2018
1	dehydroalanineIBA 12/2017
1	dehydrobutyrineIBA 12/2017
1	Amino Acids FDA Link 12/2017
1	Phosphothreonine (Threonine Phosphate)IBA 12/2017
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 10/2017
1	Tight Junction ProteinsIBA 10/2017
1	PolyphenolsIBA 10/2017
1	Antimicrobial PeptidesIBA 10/2017
1	PrebioticsIBA 10/2017
1	Rosiglitazone (Avandia)FDA Link 10/2017
1	Immune Checkpoint InhibitorsIBA 08/2017
1	AntitoxinsIBA 01/2017
1	Tetanus Toxoid (Vaccine, Tetanus)FDA Link 04/2016
1	aluminum sulfate (alum)IBA 04/2016
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 02/2016
1	Glucose (Dextrose)FDA LinkGeneric 01/2016
1	Eukaryotic Initiation Factor-3IBA 01/2016
1	Pattern Recognition ReceptorsIBA 01/2016
1	eIF-4BIBA 01/2016
1	TubulinIBA 01/2016
1	ConnexinsIBA 12/2013
1	Adenosine Triphosphate (ATP)IBA 12/2013
1	MucinsIBA 10/2013
1	Interleukin-10 (Interleukin 10)IBA 04/2013
1	Interleukin-22 (IL-22)IBA 01/2012
1	Interleukin-17 (Interleukin 17)IBA 01/2012
1	Phosphoinositide PhosphatasesIBA 09/2011
1	AntigensIBA 05/2011
1	NLR ProteinsIBA 02/2011
1	heptanoyl- gamma- D- glutamyl- L- meso- diaminopimelyl- D- alanineIBA 04/2010
1	NF-kappa B (NF-kB)IBA 02/2009
1	Cyclophilins (Cyclophilin)IBA 02/2009
1	Immunoglobulin G (IgG)IBA 02/2009
1	UbiquitinIBA 12/2008
1	Ligases (Synthetase)IBA 12/2008
1	Antimicrobial Cationic PeptidesIBA 05/2008
1	beta-DefensinsIBA 05/2008
1	Peptide Hydrolases (Proteases)FDA Link 04/2008
1	Shiga toxin subunit AIBA 02/2008
1	Polytetrafluoroethylene (Teflon)FDA Link 02/2008